ABSTRACT
Objective To analyze the status of mycoplasma infection and drug resistance in the local area,and provide the ba-sis for clinical rational drug use.Methods The specimens obtained from 1 9 530 patients with urogenital tract infection were detec-ted by adopting mycoplasma culture,identification and drug sensitivity integration kit.Mycoplasma infection and drug susceptibility were analyzed.Results In the total of 1 9 530 suspected patients specimens,1 1 1 78 cases were positive with a positive rate 57.24%.The positive rate of ureaplasma urealyticum (Uu)and mycoplasma hominis (MH)was 44.63% and 0.44% respectively and the positive rate of Uu and Mh mixed infection was 12.1 7%.The positive rate of female was higher than that of male and the difference was statistically significant(P <0.05).The positive rate of mycoplasma in 2008-2014 was on the rise;The sensitive rate of mycoplasma to josamycin,doxycycline,minocycline element,clarithromycin was 88.57%,84.32%,76.09% and 71.53% respec-tively,mycoplasma was highly drug resistance to quinolone antibiotics;mixed infection resistance was higher than that of single in-fection;The number of drug resistance of Uu,MH and Uu+MH to 12 kinds of antibiotics increase.Conclusion Mycoplasma infec-tion in urogenital tract is mainly caused by Uu and Mh infection is in mixed infection way;josamycin,doxycycline is the first choice for treatment of mycoplasma in this region.Rational drug choise can be based on the drug susceptibility test.Multiple drug resist-ance of mycoplasma is serious and should be paid attention to.
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the correlation between human immunodeficiency virus (HIV) and the sexual behaviors of men who have sex with men (MSM) in Guangzhou in 2010.</p><p><b>METHODS</b>Anti-HIV antibody was detected in the volunteers undergoing HIV tests in the year 2010, and the differences in the sexual role, education, use of condom and complicated infection of syphilis were analyzed among these subjects.</p><p><b>RESULTS</b>A total of 1526 MSM volunteered to participate in the investigation, among whom 87 (5.70%) were confirmed to have HIV infection. The positivity rate of HIV infection was 3.54%, 7.14% and 6.70% in subjects reporting active anal copulation, passive anal copulation, and both, respectively, showing a significant difference in respect of the sexual role (χ(2)=6.450, P=0.040). The positivity rate also differed significantly among married, unmarried and divorced subjects (9.45%, 4.92%, and 4.17%, respectively; χ(2)=7.184, P=0.028). The positivity rate was 21.31% among those with syphilis, significantly higher than the rate in those without syphilis (5.06%, χ(2)=25.770, P<0.001). Use of condom was not associated with a significant reduction of HIV positivity rate (P>0.05).</p><p><b>CONCLUSION</b>The high anti-HIV positivity rate among MSM in Guangzhou indicates a high risk of unsafe sexual behaviors, especially anal copulations. The anal copulation receivers, often young and have a lower rate of condom use, constitute a high-risk group of HIV transmission.</p>